Pharmaceutical Chemistry I
This is the first of the two pharmaceutical chemistry course units and it discusses drug standardization and drug quality, drug quality assurance, inorganic pharmaceutical chemistry, and the chemistry of organic pharmaceuticals. Emphasis is placed on synthesis, structure-activity relationships, analysis, and storage of these types of drugs.
PURPOSE OF THE COURSE
This course exposes
the students to practical concepts of pharmaceutical quality assurance. It also
enables them to understand the synthesis and analysis of inorganic
pharmaceutical drugs. It further enables them to appreciate the synthesis and
structure-activity relationships (SAR) of organic pharmaceutical drugs.
EXPECTED LEARNING OUTCOMES
At the end of this course, the student is expected to:
the various compendia used for controlling the quality of pharmaceutical
the possible sources of impurities in pharmaceuticals
the processes that lead to chemical and physical instability in pharmaceuticals
the process of standardization of active pharmaceutical ingredients and
the various limit tests in pharmaceutical chemistry
the physico-chemical properties of inorganic pharmaceutical preparations.
the production/synthesis, assay, identification and quality control of
inorganic pharmaceutical preparations.
the medical uses of inorganic pharmaceutical preparations.
the source, structure determination, classifications, synthesis, and
structure-activity relationship of antibiotic, anti-neoplastic agents,
anti-helminthic agents and antimalarials.