Biochemistry refers to the study of the chemistry of living organisms, at cellular and sub cellular levels. It describes in molecular terms the structures, mechanisms and chemical processes shared by all organisms and provides organizing principles that underlie life in all its diverse forms, principles collectively referred to as “the molecular logic of life”. This is through the study of the structures and functions of biomolecules and how these characteristics can contribute to physiological functions, how these biomolecules are metabolized in the body and how a disturbed metabolic profile can contribute to the onset and progress of a pathological condition.
Biochemical studies have illuminated many aspects of health and disease, and, conversely, the study of various aspects of health and disease has opened up new areas of biochemistry. This relationship between medicine and biochemistry has important philosophical implications for the former.As long as medical treatment is firmly grounded in a knowledge of biochemistry, the practice of medicine will have a rational basis that can be adapted to accommodate new knowledge. As all diseases are manifestations of abnormalities of molecules, chemical reactions, or processes. Hence knowledge about pharmacology is must have for any intending clinician including clinical officers.
This course introduces the students to the cell as the basic unit life and the compartments where various biochemical reactions occur. It covers basic principles of water and electrolytes, pH and the body‟s acid base balance. It also introduces basic biochemical principles in terms of structure and function of biomolecules; carbohydrates, lipids, nucleic acids and proteins. It examines the various vitamins and their roles as coenzymes, the various minerals and their functions and associated deficiencies. The concept of enzymes as biological catalysts is also introduced.
Course learning outcomes
As a result of studying the course, students will be able to;
a) Describe and summarize the molecular and functional organization of cells.
b) Qualitatively identify the biomolecules in biological samples