Evaluation of the anti-bacterial activity of aqueous leaf extract of Phyllanthus amarus on Streptococcus pyogenes for the treatment of tonsillitis
Phyllanthus amarus belongs to the Euphorbiaceae family, it is a tiny herb that is known forits medical benefits and used widely globally. It is also an essential plant in the IndianAyurveda medical system, and is used to treat stomach, genitourinary, liver and kidneyproblems and disorders. It is an astringent with bitter, stomachic, diuretic, febrifuge, andantiseptic in gonorrhea, menorrhagia, and other genital disorders, the entire plant isemployed in eastern Asia for the treatment of infections. It helps with gastritis, diarrhea,dysentery, intermittent fevers, scabies, ulcers, and wounds. The present study aimed ataddressing its activity against Streptococcus pyogenes for the treatment of tonsillitis and alsoit’s potential as a possible source of new antimicrobial product for tonsillitis. Distilled water(maceration method) was used in the extraction of aqueous leaf extracts of Phyllanthusamarus. Different phytochemical screening techniques were used to identify thephytochemicals present in the aqueous leaf extract of Phyllanthus amarus. The Agar welldiffusion and broth dilution test methods were used to test for the in-vitro anti-bacterialactivity of the aqueous leaf extract of Phyllanthus amarus against Streptococcus pyogenes.The percentage yield of Phyllanthus amarus aqueous leaf extracted was 13.88% (83.3mg).From the results of this research Phyllanthus amarus could be a good source for future drugdevelopments, from the aqueous leaf extract of Phyllanthus amarus in order to address theissue of need for new antibiotics due to the alarming burden of antimicrobial resistance.