Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

2023 Faculty of Clinical Medicine and Dentistry INOSR Experimental Sciences

Understanding the Drivers Behind Neonatal Sepsis Rates among Immunized and Outpatient Neonates at Hoima Regional Referral Hospital, Western Uganda

Mpanga Derick Denis

Neonatal sepsis is a major cause of neonatal mortality in developing countries, accountingfor a significant portion of annual infant deaths. This study investigated the determinantsinfluencing the occurrence of neonatal sepsis among infants at Hoima Regional ReferralHospital in Western Uganda. The study revealed an overall neonatal sepsis prevalence of12.5%, with 65% and 35% of cases classified as early-onset and late-onset sepsis,respectively. Factors significantly associated with neonatal sepsis included neonatal age,maternal history of fever, dysuria, and maternal/caretaker hygiene. The study emphasizesthe importance of caretaker/mother's age, maternal fever history, dysuria, and hygiene incontributing to neonatal sepsis. Prevention strategies should prioritize addressing theserisk factors rather than solely focusing on post-occurrence treatment. Proactive measuresare advocated to mitigate the incidence of neonatal sepsis.Keywords: Neonatal sepsis, Immunization, Childhood mortality, Maternal/caretaker’shygiene, maternal history of fever.