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2023 School of Allied Health Sciences NEWPORT INTERNATIONAL JOURNAL OF BIOLOGICAL AND APPLIED SCIENCES

Current Advances in the Diagnosis and Treatment of Sickle Cell Anaemia

Hauwa Ali Buhari1, Aisha Sa’ad Ahmad1 and *Emmanuel Ifeanyi Obeagu2

Sickle cell anemia (SCA) presents a complex challenge globally due to its significant morbidity and mortality. Recentadvancements in diagnostic tools and treatment modalities have revolutionized the management of this hereditaryhemoglobin disorder. This paper aims to synthesize current breakthroughs in the diagnosis and treatment of sicklecell anemia. Diagnostic techniques including genetic testing, hemoglobin electrophoresis, and advanced imagingmethodologies are explored, providing insights into their accuracy and clinical applicability. Moreover, noveltherapeutic approaches such as gene editing, fetal hemoglobin induction, and targeted therapies are discussed fortheir potential in ameliorating SCA-related complications and improving patient outcomes. The paper also assessesthe challenges and future prospects in the field, emphasizing the need for comprehensive strategies that encompassearly detection, personalized interventions, and ongoing research efforts. Understanding these recent strides in bothdiagnostics and therapeutics is pivotal in enhancing the care and prognosis of individuals afflicted with sickle cellanemia.Keywords: sickle cell anaemia, anaemia, treatment, diagnosis