Comprehensive Review of Antiretroviral Therapy Effects on Red Blood Cells in HIV Patients
Antiretroviral therapy (ART) has revolutionized the landscape of HIV treatment, substantiallyreducing morbidity and mortality rates in affected individuals. However, while ARTeffectively suppresses viral replication and restores immune function, its impact on redblood cells (RBCs) and associated hematological parameters has drawn increasing attentionin clinical research. This paper aims to provide a comprehensive overview of the effects ofART on RBCs among HIV patients, encompassing alterations in RBC indices, hemoglobinlevels, and potential clinical implications. A systematic review of literature and clinicalstudies was conducted to analyze observed changes in RBC parameters in individualsreceiving ART. The clinical implications arising from ART-induced changes in RBCs,particularly the occurrence of anemia and erythrocyte disorders, highlight the importance ofvigilant monitoring and tailored management strategies. Addressing these hematologicalcomplications is pivotal for optimizing treatment outcomes and enhancing patient wellbeing.In conclusion, while ART has significantly improved HIV management, its effects onRBCs signify the need for tailored monitoring and interventions to manage hematologicalcomplications effectively.Keywords: Antiretroviral Therapy, Red Blood Cells, HIV