Publications

Gilbert’s syndrome (GS) is an extensively mild condition characterized by periods of elevated levels of bilirubin inthe blood. The bilirubin is an orange yellowish tinted molecule which is produced when red blood cells are brokendown and this substance is eliminated from the body only after it undergoes bio-transformation in the liver whichconverts unconjugated bilirubin to conjugated bilirubin. When the level of unconjugated bilirubin increases beyonda determined point, the bilirubin pigment starts to discolour the cornea of the eyes (making them to appear lightyellow) and with higher levels the skin may also turn to yellow (jaundice). Gilbert’s syndrome also known asconstitutional hepatic dysfunction and familial non haemolytic jaundice. People with Gilbert’s syndrome have aninherited abnormality that causes reduced production of an enzyme involved in processing of bilirubin. Apresumptive diagnosis of Gilbert’s syndrome is made when unconjugated hyperbilirubinemia is noted on severaloccasions.Keywords: Gilbert’s syndrome, bilirubin, jaundice.