Publications

Pregnancy complications present signi􀏐icant challenges, impacting maternal health and fetaldevelopment. Oxidative stress, a key contributor to various pregnancy-related disorders suchas preeclampsia, gestational diabetes mellitus (GDM), and preterm birth, has spurred interest inexploring antioxidant interventions. Antioxidants, known for their ability to counteract oxidativedamage, have emerged as potential therapeutic agents to mitigate these complications. Thispaper synthesizes current knowledge on the role of antioxidants in pregnancy, elucidating theirmechanisms of action, sources, and impact on oxidative stress-related complications. It examinesdiverse antioxidant compounds, including vitamins C and E, selenium, and natural phytochemicals,highlighting their potential to modulate oxidative stress pathways and promote maternal-fetal wellbeing.Furthermore, this paper critically analyzes clinical studies, meta-analyses, and preclinicalresearch exploring the ef􀏐icacy and safety of antioxidant supplementation during pregnancy. Itdiscusses the complexities surrounding optimal dosages, timing, and formulations of antioxidants,aiming to delineate strategies for their integration into prenatal care. In conclusion, this reviewprovides insights into the promising role of antioxidants as therapeutic strategies to alleviatepregnancy complications associated with oxidative stress. It highlights avenues for future research,advocating for a deeper understanding of antioxidant mechanisms and their optimal utilization inprenatal care to enhance maternal and fetal health outcomes.