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2024 Faculty of Clinical Medicine and Dentistry IDOSR JOURNAL OF EXPERIMENTAL SCIENCES

Prevalence and risk factors of Preterm Births in Northern Uganda: A Hospital-Based Study at Lira Regional Referral Hospital

Omach Joshua

This study aimed to assess the prevalence, proportions of early and late preterm births, and factors associated withpreterm births among women delivering at Lira Regional Referral Hospital in Northern Uganda. It was a hospitalbasedcross-sectional observational and analytic study involving 382 women and their babies, with data collectedvia questionnaires and analyzed using STATA software version 14.0. Univariate analysis, as well as bivariate andmultivariate logistic regression, were conducted to identify factors associated with preterm birth. The mean age ofparticipants was 25.22 years, ranging from 16 to 40 years. The study found a preterm birth prevalence of 16.23%(95% CI: 12.52 – 19.94), with 66.13% (95% CI: 54.01 – 78.25) of preterm births categorized as late preterm and33.87% (95% CI: 21.75 – 45.99) as early preterm. Factors independently associated with preterm birth includedmaternal age of 16 – 23 years (aOR 6.90, 95% CI: 2.08 – 22.94, P=0.002), antepartum hemorrhage (aOR 4.75, 95%CI: 1.82 – 12.40, P=0.001), prolonged pre-labor rupture of membranes (PROM) (aOR 5.70, 95% CI: 2.00 – 16.21,P=0.001), hemoglobin level <10g/dl (aOR 20.64, 95% CI: 6.19 – 68.89, P<0.001), and hypertension (aOR 7.51, 95%CI: 2.72 – 20.75, P<0.001). In conclusion, the preterm birth rate at Lira Regional Referral Hospital was 16.23%,with maternal age, antepartum hemorrhage, prolonged PROM, low hemoglobin levels, and hypertension identifiedas significant risk factors. Recognizing these risk factors can enhance awareness of high-risk pregnancies, improvepreventive measures, and modify preterm care protocols in neonatal units.Keywords: Preterm births, Women, Maternal age, haemorrhage, Haemoglobin.