Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

2024 School of Allied Health Sciences Haematology International Journal

The Impact of HIV Infection on Eosinophil Levels during Pregnancy: A Narrative Review

Emmanuel Ifeanyi Obeagu1* and Getrude Uzoma Obeagu2

Human Immunodeficiency Virus (HIV) infection poses unique challenges during pregnancy, affecting maternal health andpotentially impacting the developing fetus. This systematic review explores the intricate relationship between HIV andeosinophils, a critical component of the immune system, during pregnancy. As HIV induces immunosuppression, understandingits specific effects on eosinophil levels is crucial for predicting maternal health outcomes and vertical transmission risks. Thereview also delves into the potential influence of antiretroviral therapy on modulating eosinophil function. By synthesizingexisting literature, this review aims to provide a comprehensive understanding of the complex interplay between HIV infection,eosinophils, and pregnancy, offering insights for future research directions and potential therapeutic interventions.Keywords: HIV Infection; Eosinophils; Pregnancy; Immunosuppression; Maternal Health; Vertical Trans