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2024 Faculty of Business and Management IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS

Advances in Analytical Techniques and Therapeutic Applications of Phytochemicals

1Chimezie O. Onukwuli, 2Chisom E. Izuchukwu and 3Ugwu Okechukwu Paul-Chima

The attentiveness towards phytochemicals, which represents the group of biologically active compounds derivedfrom plants, also referred to as phytocomponents, and has sprung up due to their therapeutics implications. Thisreview article encourages researchers to appreciate the most recent innovations in analytical approaches to thedetermination and measurement of phytochemicals, methods such as spectroscopy, chromatography and massspectrometry are some of the techniques examined here. Moreover, it covers the bioactivity and mechanisms ofaction of phytochemicals, the effect of which is their being directing to molecular targets and leading to a modulationof cellular signaling network. The way that the plant-derived compounds are absorbed, distributed, metabolized andexcreted (pharmacokinetics) and the way that they act on the body (pharmacodynamics) are examined in details andthey are found to be efficient for treating many diseases. Drug discovery and development also include a range ofinterdisciplinary fields such as chemistry, pharmacology, and other disciplines. In these areas, research includes alsoindustry considerations and ethical practices. This overview covers the range of achievements based onphytochemical research in the current stage and the expectations on its prospective influence on health care.Keywords: Phytochemicals, Analytical Techniques, Bioactivity, Pharmacokinetics and Pharmacodynamics.