Publications

Globally, acute appendicitis, requiring emergency surgery, occurs in 7 to 22 cases per 10,000 persons. The study aimed to assess the correlation between acute appendicitis and serum bilirubin. This was observational prospective cohort study, conducted in Western Uganda from November 2023 to January 2024, involved 62 adult patients diagnosed with acute appendicitis. Eligibility was determined by an Alvarado score exceeding 7. Serum levels of bilirubin were measured, with hyperbilirubinemia defined as >1.1 mg/dl for total bilirubin. Intraoperative severity of appendicitis was compared with biomarker levels. Hyperbilirubinemia was evident in 35.5% (95% CI: 23.7-48.7%). Elevated serum procalcitonin and bilirubin are observed in patients with acute appendicitis. The presence of heightened bilirubin levels is significantly associated with complicated appendicitis