Publications

The relentless global impact of Human Immunodeficiency Virus (HIV) underscores the urgency of understanding theintricate immune responses involved in its progression. CD8 T cells play a central role in orchestrating the immunedefense against HIV, wielding the potential to both curtail viral replication and, paradoxically, succumb toexhaustion. This comprehensive review explores the multifaceted engagement of CD8 T cells in HIV pathogenesis. Itencompasses the mechanisms underlying CD8 T cell recognition, the protective effects they exert, factors influencingtheir efficacy, and the emerging landscape of CD8-focused therapeutic interventions. Delving into the delicatebalance between immune defense and viral evasion, this review seeks to provide a nuanced understanding of CD8 Tcell involvement in HIV progression and illuminate the prospects for future therapeutic advancements.Keywords: HIV,