Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

2024 School of Allied Health Sciences Elite Journal of HIV

Unraveling the Immunological Nexus: Implications of Monocytes in the Context of HIV and Fibroids - A Critical Review

*Emmanuel Ifeanyi Obeagu1, Chioma Ibe2, Chinyere Nkemjika Anyanwu3 and Getrude Uzoma Obeagu4

This critical review investigates the intricate interplay between monocytes, HIV, and fibroids, aiming to unravel the immunological complexities that influence disease progression in women. The paper critically examines existing literature, highlighting the multifaceted role of monocytes and their implications on the pathogenesis of both HIV and fibroids. Special attention is given to the impact of monocytes on disease progression, offering critical insights into their role as key orchestrators in the complex relationship between HIV and fibroids. Furthermore, the review explores the immunomodulatory potential of monocytes, providing a critical assessment of therapeutic strategies that target monocyte-mediated pathways. The analysis includes a balanced critique of current challenges and gaps in understanding, along with suggestions for future research directions. In conclusion, this review underscores the crucial role of monocytes in shaping the immunological landscape of HIV-positive women with fibroids and emphasizes the need for continued research to uncover novel therapeutic interventions at the intersection of women's health, HIV, and fibroids.