Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

2024 School of Allied Health Sciences Elite Journal of Haematology

Unraveling the Puzzle: COVID-19's Influence on Hemostasis Mechanisms

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

In the wake of the global COVID-19 pandemic, a growing body of evidence underscores the intricate relationship between the virus and hemostasis mechanisms, unraveling a complex puzzle that demands attention from both the medical and scientific communities. This review article delves into the multifaceted impact of COVID-19 on hemostasis, shedding light on the virus's influence on coagulation pathways, platelet function, and vascular dynamics. Keywords such as thrombosis, fibrinolysis, and endothelial dysfunction take center stage as we explore the intricate dance between the SARS-CoV-2 virus and the body's clotting mechanisms. With a focus on recent research findings, clinical observations, and potential therapeutic interventions, this review aims to provide a comprehensive overview of the evolving understanding of COVID-19's effects on hemostasis. As we navigate this challenging intersection of infectious disease and coagulation biology, unlocking the mysteries of COVID-19's influence on hemostasis is crucial for informing clinical management strategies and advancing our broader understanding of viral pathogenesis.