Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

2024 School of Allied Health Sciences International Journal of Current Research in Medical Sciences

Gestational Diabetes and Neutrophil Activation: A Cellular Symphony

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

Gestational diabetes mellitus (GDM) represents a complex metabolic disorder during pregnancy, impacting bothmaternal and fetal health. Recent investigations have shed light on the intricate interplay between gestational diabetesand neutrophil activation, revealing a cellular symphony that contributes to the pathophysiology of this condition.This review explores the current state of knowledge regarding the relationship between gestational diabetes andneutrophil activation, focusing on the molecular mechanisms, immune responses, and inflammatory cascades thatorchestrate this cellular symphony. Understanding these interactions is crucial for unraveling the complexities ofgestational diabetes and may pave the way for novel therapeutic interventions aimed at mitigating the associatedinflammatory burden and improving pregnancy outcomes.