Exploring the Antibacterial Properties of Carica papaya Unripe Fruit Extracts on Wound Isolates: Phytochemical Analysis and Susceptibility Testing
The rise of multidrug-resistant bacterial pathogens poses a significant challenge in wound management. In thisstudy, we investigated the phytochemical constituents and antibacterial properties of unripe fruit extracts of Caricapapaya on bacterial isolates from wounds. Phytochemical analysis revealed the presence of phenols, tannins,saponins, alkaloids, terpenoids, reducing sugars, and cardiac glycosides in both aqueous and 50% ethanolicextracts. Antimicrobial susceptibility testing demonstrated significant activity against Staphylococcus aureus,Protues vulgaris, Enterobacter aerogenes, and Escherichia coli, with aqueous extract exhibiting greater inhibitionthan the ethanolic counterpart. However, no activity was observed against Pseudomonas aeruginosa. These findingsunderscore the potential of Carica papaya extracts in combating opportunistic infections in wound management.