Publications

Isoniazid Preventive Therapy (IPT) is a proven intervention for preventing the development of active tuberculosis(TB) in people living with HIV (PLHIV). However, despite its effectiveness, the uptake of IPT among PLHIVremains low, especially in resource-limited settings such as Ntungamo district in Uganda. To determine theknowledge, attitude, and practices towards the use of isoniazid preventive therapy (IPT) among HIV-positivepatients at Itojo Hospital, Ntungamo District. This descriptive cross-sectional study aimed to assess theknowledge, attitudes, and practices of IPT among HIV-positive patients attending Itojo Hospital in Ntungamodistrict. We recruited a total of 50 participants using simple random sampling, and collected data using astructured questionnaire. We used descriptive statistics and logistic regression to analyze the data and determinethe likelihood of the outcomes. The study involved 50 participants who volunteered. It was depicted that femalegender (p-value: 0.016, aOR: 2.59 (0.63–10.71)), age of 31–35 years (p-value: 0.016, aOR: 0.17 (0.02-1.51) andtertiary level of education (p-value: 0.025, aOR: 1.76 (0.31–9.46)) were significant predictors of knowledge.Primary level education (p-value: 0.02, aOR: 1.28(0.34-4.85)) and unemployment (p-value: 0.05, aOR: 0.22(0.05-1.01)) were significantly associated with attitudes towards the use of IPT among HIV-positive patients at ItojoHospital. Age of 26–30 years (p-value: 0.003, aOR: 4.427(0.068–288.290)) and secondary level of education (pvalue:0.046, aOR: 1.23(0.961–1.565)) were significantly associated with the practices towards the use of IPTintake. The study identified age, gender, and level of education as significant predictors of knowledge, attitude, andpractices towards the use of IPT intake among HIV-positive patients at Itojo Hospital. The findings indicate theneed for improved education and awareness campaigns on IPT intake among PLHIV in Ntungamo district.Addressing concerns related to side effects and improving access to health facilities could also increase the uptakeof IPT. These findings can inform the development of targeted interventions to improve the uptake of IPT amongPLHIV in resource-limited settings