2024 Faculty of Biomedical Sciences NEWPORT INTERNATIONAL JOURNAL OF BIOLOGICAL AND APPLIED SCIENCES (NIJBAS) CRISPR-Cas9 Mediated Gene Editing for Targeted Cancer Therapy: Mechanisms, Challenges, and Clinical Applications 1Ugwu Okechukwu Paul-Chima, 2Anyanwu Chinyere Nkemjika, 1Alum Esther Ugo, 1Okon Michael Ben, 1Egba Simeon Ikechukwu, 1Uti Daniel Ejim and 3Awafung Emmanuel Adie