Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

2023 Faculty of Biomedical Sciences IDOSR JOURNAL OF EXPERIMENTAL SCIENCES

A Review on Cimetidine and its Toxicological Effects on Male Reproductive System

Ikuomola, Emmanuel Orire

Cimetidine is recommended for the treatment of chronic peptic ulceration, haemorrhage from erosive gastritis, and the control of gastric hypersecretion and peptic ulceration in the Zollinger-Ellison syndrome, cimetidine1 is a specific competitive histamine H2-receptor antagonist that effectively inhibits gastric acid secretion. Therefore, this review further highlights the mechanisms of action, adverse effect profile, and other significant elements important to the interprofessional team members in patient management utilizing cimetidine.