Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

2025 School of Pharmacy IDOSR JOURNAL OF EXPERIMENTAL SCIENCES

Narrative Review of Interventions to Reduce Maternal and Neonatal Mortality

Arionget Jemima

Maternal and neonatal mortality rates remain unacceptably high across low- and middle-income countries (LMICs), despite the availability of effective, evidence-based interventions. This narrative review synthesizes findings from studies published between January 2000 and March 2022, examining health system and policy interventions that enhance access to skilled maternal and newborn care. The review identifies four primary implementation domains: health system and policy factors; equity, access, and contextual determinants; knowledge-seeking, demand, and supply influences; and service-design measures. Key antenatal interventions include risk screening and management, nutritional supplementation, infectious disease screening, and vaccination. Intrapartum and delivery-related interventions encompass skilled birth attendance, emergency obstetric and newborn care (EmONC), cesarean section, uterotonic drug administration, and intrapartum fetal monitoring. Postpartum and neonatal interventions such as newborn resuscitation, thermal protection, infection control, and early breastfeeding support significantly reduce mortality risk. Effective implementation of these interventions depends on a strong health workforce, well-equipped facilities, reliable supply chains, and community-based outreach. Persistent inequities rooted in poverty, gender norms, and urban–rural disparities continue to limit access to quality care. Evidence underscores the need for integrated, context-sensitive strategies and policies that strengthen health systems, enhance community engagement, and ensure equitable access to skilled services. Strengthening maternal and newborn care delivery within resilient health systems offers a clear pathway toward achieving global maternal and neonatal mortality reduction targets.