Publications

Arthritis is a leading cause of chronic pain, disability, and reduced quality of life globally, with significant prevalence in Nigeria. Patients with arthritis frequently experience comorbid depression and anxiety, which exacerbate pain perception, impair functional ability, reduce treatment adherence, and worsen overall outcomes. This review synthesizes current evidence on the prevalence, risk factors, mechanisms, and clinical consequences of depression and anxiety among arthritis patients in Nigeria. Findings indicate high rates of psychological distress, influenced by biopsychosocial factors including pain severity, functional limitations, disease duration, social support, and systemic inflammation. Health-system challenges, sociocultural barriers, and limited mental health resources further compound the burden. Effective management requires integrated biopsychosocial approaches, routine mental health screening, culturally validated tools, task-shifted psychological interventions, rehabilitation support, and strengthened healthcare policies. Identified research gaps highlight the need for population-based studies, longitudinal research, and locally adapted interventions. Addressing these challenges is crucial to optimizing arthritis care, reducing disability, and improving quality of life in the Nigerian context.