Publications

Methicillin-resistant Staphylococcus aureus (MRSA) is spreading around the world, with prevalence ranging from 23.3% to 73 %. This study, therefore, evaluated the antibacterial activity of a combination of crude juice extracts of Alliumsativum and Curcuma longa against methicillin-resistant Staphylococcus aureus. The combined crude juice extractsexhibited moderate antibacterial activity against methicillin-resistant Staphylococcus aureus, which was determinedby the agar well diffusion method where the Allium sativum crude juice extract revealed a high level of antibacterialactivity with the highest mean and standard error of the mean inhibition zone diameters of 21.67 ± 0.88 mm atconcentration 100%v/v compared at a concentration of 50%v/v which showed a mean and standard error of themean inhibition zone diameter of 21.33 ± 0.67 mm. On the other hand, Curcuma longa crude juice extract didn’t showany antibacterial activity against the test organism. The minimum inhibitory concentration (MIC) of thecombination of the crude juice extracts of Allium sativum and Curcuma longa crude juice extracts was 25%v/v, Alliumsativum was 25%v/v w and Curcuma longa was 0%v/v. The minimum bactericidal concentration (MBC) results thatthe study extract was bacteriostatic since all used concentrations showed visible growth after overnight incubation.The FIC of the extract was 1 hence there was an additive antibacterial effect of the extract combination.