Publications

These interactions affect the diagnosis, treatment, prognosis, and general healthcare of the patients with bothconditions. Although HIV and SCD coexist, few properly designed studies show systematic investigation into theirinteraction. The evidence that is available and is presented in this review shows that SCD slows the progression ofHIV into AIDS but that, on the other hand, HIV worsens SCD; drugs for treating both diseases interact with eachother and the respective diseases; and both diseases are risk factors for certain diseases such as stroke, avascularnecrosis, severe splenic dysfunction, PAH, and sepsis, which could synergistically increase the odds of getting thosediseases. Properly documented information on this has the potential to inform national health policies in these areas,many of which are developing countries. There is therefore the need for further research on the impact of thiscontemporaneity on the health and well-being of individuals and their families, as well as society as a whole