Publications

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2023 School of Pharmacy INOSR APPLIED SCIENCES

Evaluation of the Adverse Drug Reaction Reporting System at IV and 111 Hospitals and Health Centers in Bushenyi District

Nakajiri Somaiya; Arafhart Kibirige; Kimbowa John; Kabanza Robert; Kayima Ronald

Currently, adverse drug reactions are the 6th leading cause of death worldwide. In sub-Saharan Africa, 6.3% of hospitalizations are a direct result of adverse drug reactions. Thisstudy aimed to evaluate the adverse drug reaction reporting system at Hospitals and HealthCenters IV and III in Bushenyi District. A cross-sectional study was conducted on 225 healthprofessionals including pharmacists, trainee pharmacists, nurses, midwives, trainee nurses,physicians and internists, followed by agents clinical. Data collected using questionnaireswere entered into SPSS version 25 for analysis. The analyzed information is presented intables and graphs. The results indicated that 80 (35.6%) were from Kampala InternationalUniversity Teaching Hospital, the majority 132 (58.7%) were between the ages of 26 and 45,of which 121 (53.8%) were female and 104 (45.3%) were male. The majority, 98 (43.6%) werecertified and 117 (52.0%) were nurses. The majority of medical facilities, 164 (72.9%), had asystem for reporting adverse drug reactions and 50 (22.2%) said they did not have thissystem. 160 (71.1%) respondents discovered side effects of the medication. Of these, 133(83.1%) reported these reactions and 27 (19.9%) did not report adverse drug reactions. Almost95 (59.4%) adverse drug reactions were reported to physicians, 30 (18.6%) to pharmacists,and finally 3 (2.3%) to NDAs. In summary, adverse drug reaction reporting systems exist, withadverse drug reaction reporting forms being the most common adverse drug reactionreporting tool. Healthcare professionals who had heard about an adverse drug reaction were12 times more likely than other healthcare professionals to report an adverse drug reaction.Additionally, the lowest adverse drug reaction reporting rates were recorded at IshakaAdventist Hospital and Comboni Hospital. Most medical staff have detected adverse drugreactions and 83.1% of them reported adverse drug reactions but sent them to the wrongauthorities (doctors, pharmacists), mainly through phone. As a result, the National DrugAuthority (NDA) pharmacovigilance center, pharmacovigilance coordinators at regionalhospitals and online platforms were not used properly.