Publications

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2023 School of Allied Health Sciences IDOSR JOURNAL OF SCIENTIFIC RESEARCH

Neonatal Sepsis: Haematological Perspectives

Emmanuel Ifeanyi Obeagu; Ndakize Benjamin Kigabo; Getrude Uzoma Obeagu; Okechukwu Paul-Chima Ugwu; Sophia Kazibwe

Neonatal sepsis (NS) is a leading cause of neonatal morbidity and mortality and is considereda global public health challenge. The organisms and pathogens most commonly associatedwith neonatal sepsis vary by country. Pathogens range from Gram-positive and Gramnegativebacteria to viruses and fungi, with bacteria being the most commonly identified.Bacteria most commonly involved include Staphylococcus aureus, coagulase-negativestaphylococci (CONS), Streptococcus pneumoniae, Streptococcus pyogenes, Escherichia coli,Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, and Group BStreptococcus increase, or urine culture is usually delayed for a day or two. A battery of tests,including C-reactive protein, total leukocyte count, absolute neutrophil count, platelet count,neutrophil cytoplasmic vacuolization, and polymorphic gastric aspiration cytology, wasperformed in neonates with a clinical diagnosis of NS. It's an excellent screening tes