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2024 School of Allied Health Sciences

Eosinophil Count Fluctuations during Pregnancy in Women with HIV: A Comprehensive Review

Emmanuel Ifeanyi Obeagu1* and Getrude Uzoma Obeagu2

2024 | Haematology International Journal | Pp. 1-9

Pregnancy in women with Human Immunodeficiency Virus (HIV) presents a unique set of challenges, necessitating a closerexamination of the immune system’s responses, particularly in relation to eosinophil dynamics. This comprehensive reviewexplores the fluctuat...

2024 School of Allied Health Sciences

Effect of metformin on vitamin B12 and homocysteine levels among Sudanese with type 2 diabetes mellitus

Sumaia Mohammed Ali AL-Ghaili1, Eltayeb Mohammed Ahmed Tayrab2,3 and Emmanuel Ifeanyi Obeagu4

2024 | Elite Journal of Medicine | Pp. 85-103

Metformin is the first-line treatment for type 2 diabetes mellitus (T2DM), and hyperglycemia. When taken in high doses or for an extended period, metformin may decrease vitamin B12 (VitB12) level and may increase homocysteine (Hcy) level. There has been no re...

2024 School of Allied Health Sciences

Dual Management: Diabetes and Sickle Cell Anemia in Patient Care

Emmanuel Ifeanyi Obeagu1* and Getrude Uzoma Obeagu2

2024 | Haematology International Journal | Pp. 1-7

The coexistence of diabetes mellitus (DM) and sickle cell anemia (SCA) presents a complex medical challenge, necessitating anintegrated approach to patient care. This review explores the interplay between diabetes and sickle cell anemia, addressingthe epidemi...

2024 School of Allied Health Sciences

Drug-Drug Interactions in the Management of Coexisting Sickle Cell Anemia and Diabetes

*Emmanuel Ifeanyi Obeagu1, Ebere Emilia Ayogu2,3, Chinyere Nkemjika Anyanwu4 and Getrude Uzoma Obeagu

2024 | Elite Journal of Medical Sciences | Pp. 1-9

This review scrutinizes the intricate landscape of drug-drug interactions in the management of coexisting sickle cell anemia and diabetes, two chronic conditions that often intersect, challenging healthcare providers in their pursuit of optimal patient care....

2024 School of Allied Health Sciences

Dendritic Cell Function in HIV-Infected Pediatric Populations

*Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of Immunology | Pp. 1-14

Pediatric HIV infection presents unique challenges due to the dynamic interplay between the virus and the developing immune system. Dendritic cells, key regulators of immune responses, play a crucial role in shaping the outcomes of HIV infection in children....

2024 School of Allied Health Sciences

Cytokine Modulation as a Strategy for Type 1 Diabetes Intervention: Unraveling Immunological Complexities for Therapeutic Advancements

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of Immunology | Pp. 65-75

Type 1 diabetes (T1D) stands as a formidable autoimmune challenge, marked by the progressive destruction of insulin-producing pancreatic beta cells. This review explores the potential of cytokine modulation as a strategic intervention in T1D, acknowledging th...

2024 School of Allied Health Sciences

Current Trends and Challenges in Blood Transfusion for Individuals with HIV

*Emmanuel Ifeanyi Obeagu1, Chioma Ibe2, Getrude Uzoma Obeagu3 and Chinyere Nkemjika Anyanwu4

2024 | International Journal of Innovative and Applied Research | Pp. 47-63

This review article provides an in-depth exploration of the current trends and challenges associated with blood transfusion practices in individuals living with HIV. As advancements in antiretroviral therapy (ART) have significantly improved the life expectan...

2024 School of Allied Health Sciences

Counting Cells, Shaping Fates: CD4/CD8 Ratios in HIV

*Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of Scientific Research and Review | Pp. 37-50

The dynamic interplay between CD4 and CD8 T-cell populations stands as a pivotal aspect of immune function, particularly in the context of HIV infection. The balance between CD4 and CD8 T-cell subsets is fundamental for orchestrating an effective immune respo...

2024 School of Allied Health Sciences

Clinical Implications of Neutrophil-to-Lymphocyte Ratio in Sickle Cell Disease

Emmanuel Ifeanyi Obeagu1* and Getrude Uzoma Obeagu2`

2024 | Haematology International Journal | Pp. 1-9

Sickle Cell Disease (SCD) is a hereditary hemoglobinopathy characterized by chronic hemolytic anemia and vaso-occlusiveevents. In recent years, the Neutrophil-to-Lymphocyte Ratio (NLR) has emerged as a potential biomarker with prognostic anddiagnostic signifi...

2024 School of Allied Health Sciences

Challenges and Considerations in Managing Blood Transfusion for Individuals with HIV

*Emmanuel Ifeanyi Obeagu1, Chinyere Nkemjika Anyanwu2 and Getrude Uzoma Obeagu3

2024 | Elite Journal of HIV. | Pp. 1-17

This review addresses the complex landscape of managing blood transfusions for individuals with HIV, uncovering challenges and considerations that influence patient care. As HIV has evolved into a manageable chronic condition with the advent of antiretroviral...