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5,279 results found Records are sourced from the KIU Publications module.
2024 School of Allied Health Sciences

Modulation of L-selectin Expression in Tuberculosis-HIV Coinfection: Implications for Disease Control

Obeagu EI and Onuoha EC.

2024 | Elite Journal of Public Health. | Pp. 56-74

Tuberculosis (TB) and human immunodeficiency virus (HIV) coinfection presents a complex challenge in global health, characterized by heightened disease severity and therapeutic complexities. Immune dysregulation plays a pivotal role in the pathogenesis of TB-...

2024 School of Allied Health Sciences

Climate Change as a Driver of HIV Transmission Dynamics: A Review

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of HIV | Pp. 110-127

Climate change is increasingly recognized as a multifaceted challenge with far-reaching implications for human health. Among its numerous impacts, climate change is now understood to play a significant role in shaping the dynamics of HIV transmission. This re...

2024 School of Allied Health Sciences

A Roadmap for Reducing HIV Transmission from Mother to Child: Strategies, Challenges, and Future Directions

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of HIV. | Pp. 91-109

Mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) remains a significant global health challenge, particularly in resource-limited settings. Despite remarkable progress in preventing MTCT through the implementation of comprehensive prev...

2024 School of Allied Health Sciences

Citation: Obeagu EI, Obeagu GU. Transfusion-Related Impact on Immune Modulation in Pediatric Severe Malaria Survivors with HIV: A Review. Elite Journal of Immunology, 2024; 2(4): 93-111 1 Transfusion-Related Impact on Immune Modulation in Pediatric Severe Malaria Survivors with HIV: A Review

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of Immunology | Pp. 93-111

Severe malaria and HIV co-infection represent significant health challenges in pediatric populations, particularly in regions where both diseases are endemic. Blood transfusion is often a life-saving intervention for managing severe anemia and other complicat...

2024 School of Allied Health Sciences

Transfusion-Related Acute Lung Injury in HIV-Positive Pediatric Severe Malaria Cases: A Review

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of Nursing and Health Sciences | Pp. 79-97

Transfusion-related acute lung injury (TRALI) is a severe complication of blood transfusion characterized by acute respiratory distress and pulmonary edema. In pediatric patients with severe malaria and concurrent HIV infection, TRALI represents a significant...

2024 School of Allied Health Sciences

Role of L-selectin in Tuberculosis-HIV Coinfection: Implications for Immune Activation and Dysfunction

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of HIV | Pp. 72-90

Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) coinfection pose significant challenges to global health, with intricate interactions between these pathogens influencing immune responses and disease outcomes. L-selectin, a cell adhesion molecule cruc...

2024 School of Allied Health Sciences

Transfusion-Related Alterations in Thrombopoiesis in Pediatric Severe Malaria Cases with HIV: A Review

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of Scientific Research and Re | Pp. 69-87

Severe malaria and HIV co-infection pose significant challenges in pediatric healthcare, particularly in regions where both diseases are endemic. Thrombocytopenia is a common complication of severe malaria, necessitating blood transfusion to prevent hemorrhag...

2024 School of Allied Health Sciences

Safety and Tolerance of Blood Transfusion in Severe Malaria Cases with HIV: Lessons from Pediatric Cases

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of Laboratory Medicine | Pp. 64-83

Blood transfusion is a life-saving intervention often employed in the management of severe malaria-related complications, particularly in pediatric populations. However, in regions with high HIV prevalence, the co-occurrence of HIV infection complicates trans...

2024 School of Allied Health Sciences

Citation: Obeagu EI, Obeagu GU. Transfusion-Related Complications in Pediatric Severe Malaria Cases: A Focus on HIV Coinfection. Elite Journal of Medicine, 2024; 2(4): 74-91 1 Transfusion-Related Complications in Pediatric Severe Malaria Cases: A Focus on HIV Coinfection

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of Medicine | Pp. 74-91

Transfusion therapy plays a critical role in managing severe malaria-related complications, particularly in pediatric populations. However, in the context of HIV coinfection, transfusion-related complications may exacerbate neurological vulnerabilities in aff...

2024 School of Allied Health Sciences

The Impact of Body Mass Index (BMI) on Immune Function in Leukemia Patients Living with HIV: A Review

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of Immunology | Pp. 73-92

Body mass index (BMI) serves as a crucial indicator of nutritional status and metabolic health, yet its role in modulating immune function, particularly in leukemia patients living with HIV/AIDS, remains poorly understood. This paper explores the intricate re...