Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.
Knowledge Outputs
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2024 | Elite Journal of Medicine. | Pp. 55-73
Children with severe malaria and HIV often require blood transfusions to manage complications such as severe anemia. However, the neurocognitive effects of these transfusions remain poorly understood. This review consolidates existing knowledge on the neuroco...
2024 | Elite Journal of Scientific Research and Review | Pp. 49-68
Blood transfusion is a crucial intervention in the management of severe malaria-associated anemia, aiming to improve tissue perfusion and support recovery. However, in pediatric patients with severe malaria and concurrent HIV infection, the impact of blood tr...
2024 | Elite Journal of Laboratory Medicine. | Pp. 46-63
Pediatric severe malaria, compounded by HIV co-infection, presents a complex clinical challenge, often necessitating blood transfusion for severe anemia. However, determining optimal transfusion thresholds for this population remains elusive. This review synt...
2024 | Elite Journal of Laboratory Medicine | Pp. 26-45
Obesity, leukemia, and HIV/AIDS constitute a challenging clinical triad, each with distinct pathophysiological mechanisms and clinical implications. This paper reviews the intricate relationship between obesity and overall survival in leukemia patients living...
2024 | Elite Journal of Medical Sciences | Pp. 21-39
Blood transfusion is a critical intervention in the management of severe malaria in pediatric patients, particularly in those with concurrent HIV infection. While transfusion therapy aims to improve hemoglobin levels and tissue perfusion, its impact on the qu...
2024 | Elite Journal of Medical Sciences | Pp. 1-20
Transfusion-related complications pose significant challenges in the management of children with severe malaria, HIV infection, and underlying hematological disorders. This comprehensive review examines the epidemiology, pathophysiology, clinical manifestatio...
2024 | EURASIAN EXPERIMENT JOURNAL OF SCIENTIFIC AND APPLIED RESEARCH | Pp. 31-42
Particularly in Sub-Saharan Africa, where Uganda has one of the highest incidence rates worldwide, cervicalcancer is a serious public health problem. Utilisation is still low despite national programmes that support freeHPV vaccinations and screenings. This r...
2024 | International Journal of Current Research in Medical Sciences | Pp. 10-23
Hematopoietic stem cell (HSC) dysfunction is a significant contributor to immune impairment in HIV infection.GATA-1, a pivotal transcription factor in hematopoiesis, emerges as a key regulator influencing HSC function andlineage commitment. This review explor...
2024 | EURASIAN EXPERIMENT JOURNAL OF BIOLOGICAL SCIENCES | Pp. 26-34
Typhoid fever remains a significant public health concern in Uganda, particularly in rural areas where access toclean water and sanitation facilities may be limited. Understanding the prevalence and associated factors of typhoidfever can inform targeted inter...
2024 | EURASIAN EXPERIMENT JOURNAL OF BIOLOGICAL SCIENCES | Pp. 97-104
For the best possible outcomes for the health of both the mother and the foetus, timely antenatal care (ANC) mustbe started. Delays in obtaining ANC services, however, continue to be a serious problem, especially in areas withlow resources like Western Uganda...