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2026 School of Natural and Applied Sciences

Pharmacogenomics through Proteogenomics in Primary Care: Clinical Workflows, Outcomes, and Cost Effectiveness

Kibibi Wairimu H.

2026 | RESEARCH INVENTION JOURNAL OF PUBLIC HEALTH AND PHARMACY | Pp. 20-29

Pharmacogenomics has emerged as a cornerstone of precision medicine, enabling safer and more effective prescribing through the identification of genetic determinants of drug response. Proteogenomics extends this approach by incorporating protein expression, m...

2026 School of Natural and Applied Sciences

Pharmacogenomics and Polygenic Risk Scores in National Health Insurance Systems: Clinical Workflows, Outcomes, Cost-Effectiveness, and Equity

Nambi Namusisi H.

2026 | RESEARCH INVENTION JOURNAL OF PUBLIC HEALTH AND PHARMACY | Pp. 9-19

Pharmacogenomics and polygenic risk scores (PRS) offer transformative potential for precision medicine by tailoring prevention, diagnostics, and treatment strategies to individual genetic profiles. National Health Insurance (NHI) systems provide an optimal fr...

2026 Faculty of Science and Technology

Newborn Screening Expansion Using Whole-Genome Sequencing: Benefits, Harms, and Public Health Decision Frameworks, Current Evidence and Gaps

Kato Jumba K.

2026 | RESEARCH INVENTION JOURNAL OF PUBLIC HEALTH AND PHARMACY | Pp. 1-8

The expansion of newborn screening through whole-genome sequencing (WGS) represents a transformative shift from targeted biochemical testing toward comprehensive genomic population screening. This paper examines the potential benefits, harms, and public-healt...

2026 School of Pharmacy

Newborn Screening Expansion Using Long-Read Sequencing: Benefits, Harms, and Public Health Decision Frameworks Methods, Challenges, and Future Directions

Bwanbale Geoffrey David

2026 | RESEARCH INVENTION JOURNAL OF RESEARCH IN MEDICAL SCIENCES | Pp. 110-121

The integration of long-read sequencing (LRS) into newborn screening (NBS) programs offers transformative potential for public health by enhancing diagnostic yield, resolving complex genetic variants, and providing expanded carrier and prenatal information. C...

2026 School of Pharmacy

Narrative Review of Vaccine Hesitancy Interventions

Bwanbale Geoffrey David

2026 | RESEARCH INVENTION JOURNAL OF RESEARCH IN MEDICAL SCIENCES | Pp. 104-109

Vaccine hesitancy remains a significant global public health challenge, contributing to delayed or refused vaccination despite the availability of safe and effective immunization services. This narrative review synthesizes evidence on interventions designed t...

2026 Faculty of Clinical Medicine and Dentistry

Nano-Biosensors for Early Detection of Obesity-Related Cancer Biomarkers

Omeye Francis I.

2026 | RESEARCH INVENTION JOURNAL OF RESEARCH IN MEDICAL SCIENCES | Pp. 92-96

Obesity establishes a chronic, low-grade inflammatory and endocrine milieu that elevates cancer risk and worsens outcomes across multiple organs. Early interception depends on detecting compoNsite biomarker signatures spanning inflammatory cytokines, adipokin...

2026 Faculty of Clinical Medicine and Dentistry

Nano Biosensors for Continuous Monitoring of Metabolic Biomarkers in Obese Diabetic Individuals

Omeye Francis I.

2026 | RESEARCH INVENTION JOURNAL OF RESEARCH IN MEDICAL SCIENCES | Pp. 97-103

Obesity-associated type 2 diabetes is characterized by chronic hyperglycemia, insulin resistance, dyslipidemia and low-grade inflammation, all of which fluctuate markedly in response to meals, physical activity, stress and medication use. Conventional monitor...

2026 Faculty of Science and Technology

Monoclonal Antibody Prophylaxis Against Plasmodium Falciparum Infection in High-Transmission Settings

Mugisha Emmanuel K.

2026 | RESEARCH INVENTION JOURNAL OF RESEARCH IN MEDICAL SCIENCES | Pp. 87-91

Plasmodium falciparum malaria remained a formidable public health challenge in high-transmission regions, particularly sub-Saharan Africa. Despite existing control measures, malaria continues to cause significant morbidity and mortality, underlining the urgen...

2026 Faculty of Science and Technology

Mitochondrial Dysfunction in Obesity-Associated Insulin Resistance and Diabetes Progression

Mugisha Emmanuel K.

2026 | RESEARCH INVENTION JOURNAL OF RESEARCH IN MEDICAL SCIENCES | Pp. 62-68

Mitochondria govern cellular energy, redox balance, and metabolite signaling across metabolic tissues. In obesity, chronic nutrient oversupply glucose, fatty acids, and branched-chain amino acids forces mitochondria to operate outside their adaptive ranges, t...

2026 Faculty of Biomedical Sciences

Metabolomics Profiling of Antiretroviral Therapy Associated Metabolic Syndrome in People Living with HIV

Odile Patrick Thalia

2026 | RESEARCH INVENTION JOURNAL OF RESEARCH IN MEDICAL SCIENCES | Pp. 50-61

Antiretroviral therapy (ART) has transformed HIV infection into a manageable chronic condition, yet metabolic syndrome (MetS) emerged as a critical comorbidity in people living with HIV (PLHIV), affecting 20–54% of this population compared to 10–25% in the ge...