Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.
Knowledge Outputs
Publication records can include DOI links, downloads, authors, abstracts and indexing data.
2024 | Elite Journal of Immunology
CD8 T cells are key players in the immune response against HIV, tasked with identifying and eliminating virus-infected cells. However, the battle between HIV and CD8 T cells is complex, marked by a dynamic interplay between viral evasion strategies and host i...
2024 | Elite Journal of Immunology | Pp. 18-35
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a critical immune checkpoint molecule involved in regulating T cell activation and tolerance. Genetic variations in CTLA-4 have been implicated in modulating susceptibility to human immunodeficiency viru...
2024 | Elite Journal of Health Sciences | Pp. 7-23
GATA-1 mutations have been implicated in various hematological disorders, and emerging evidence suggests their association with HIV infection, leading to a spectrum of hematological abnormalities. This review explores the role of GATA-1 mutations in HIV-assoc...
2024 | Elite Journal of Scientific Research and Review | Pp. 20-36
GATA-1, a key transcription factor, plays a crucial role in regulating megakaryocyte function and platelet production. In the context of HIV infection, dysregulation of GATA-1 signaling pathways contributes to hematologic abnormalities, including thrombocytop...
2024 | Elite Journal of Immunology | Pp. 1-17
HIV infection is associated with an increased risk of lymphomas, presenting a therapeutic challenge due to the complex interplay between immune dysfunction and tumorigenesis. The programmed cell death protein 1 (PD-1) pathway has emerged as a pivotal immune c...
2024 | Elite Journal of HIV | Pp. 1-17
Immune dysregulation is a hallmark feature of HIV/AIDS, contributing significantly to disease progression and complications. Despite advancements in antiretroviral therapy (ART), immune dysfunction persists in HIV/AIDS patients, necessitating a deeper underst...
2024 | Elite Journal of Scientific Research and Review | Pp. 1-19
Antacid use is prevalent among HIV patients due to gastrointestinal symptoms and the side effects of antiretroviral therapy (ART). This review examines the implications of antacid use in HIV patients, focusing on drug absorption, metabolism, and adverse effec...
2024 | IAA Journal of Management | Pp. 20-24
Alternative Dispute Resolution (ADR) has gained significant traction globally as a preferred method for resolvingconflicts outside traditional litigation processes. In Uganda, the legal community has embraced ADR due to itspotential benefits in expediting con...
2024 | NEWPORT INTERNATIONAL JOURNAL OF PUBLIC HEALTH AND PHARMACY | Pp. 39-48
This narrative review evaluates the implementation purposes of telemedicine in medical service delivery in thecontext of the COVID-19 pandemic. Telemedicine covering all forms of e-Delivery of healthcare has undergonemassive changes in technology, comprising...
2024 | IAA Journal of Management | Pp. 14-19
This study examines the relationship between informal sector practices and people's socio-economic status inMagharibi District-Zanzibar. Through a descriptive correlational design, data were collected from 230respondents across five sheihas. The findings reve...