Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.
Knowledge Outputs
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2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 46-50
Stress-mediated hepatotoxicity-liver injury driven or amplified by oxidative stress, endoplasmic reticulum (ER) stress, mitochondrial dysfunction, and inflammation-represents a convergent pathway for a broad range of chemical, biological and metabolic insults...
2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 1-6
Rheumatoid factor (RF), traditionally regarded as a serological marker of rheumatoid arthritis (RA), is increasingly recognized for its broader relevance in systemic inflammatory states. Accumulating evidence suggests that RF positivity may reflect underlying...
2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 98-102
Renal toxicity represents a major clinical and public health challenge, contributing substantially to the global burden of acute kidney injury and its frequent progression to chronic kidney disease. A growing body of research identifies oxidative stress and r...
2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 21-26
Herbal remedies remain widely used worldwide as adjuncts or alternatives for diabetes management. Many botanicals show promising glucose-lowering, insulin-sensitizing, anti-inflammatory and antioxidant effects in vitro, in animals and in small human trials. H...
2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 40-45
Tuberculosis (TB) unfolds within a chemically reactive battlefield where host-derived reactive oxygen and nitrogen species (ROS/RNS) intersect with immune signaling to shape disease outcomes. While oxidative stress is essential for mycobacterial control, sust...
2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 26-30
Autoimmune disorders such as rheumatoid arthritis (RA) arise from a breakdown in immune tolerance, leading to chronic inflammation, autoantibody production, and progressive tissue destruction. Among these autoantibodies, rheumatoid factor (RF)-an immunoglobul...
2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 93-97
Phytochemical antioxidants, encompassing diverse plant-derived molecules such as polyphenols, carotenoids, organosulfur compounds, and certain alkaloids, represent a crucial interface between diet and immune system regulation. While their early recognition ce...
2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 11-15
Oxidative stress and inflammation are tightly intertwined drivers of acute and chronic disease. Antioxidant phytochemicals-plant-derived polyphenols, carotenoids, organosulfur compounds and related small moleculesmodulate redox balance and reprogram immune re...
2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 47-51
Environmental toxicants, including heavy metals, particulate matter, pesticides, and industrial chemicals, constitute a major global health burden due to their ability to trigger oxidative stress and dysregulate innate immune responses. These early biological...
2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 6-10
Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia, which exerts profound effects on multiple organ systems, including the nervous system. Neurotoxicity in diabetes is increasingly recognized as a consequence of mitochondria...