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2026 Faculty of Clinical Medicine and Dentistry

Antimalarial Drug Resistance Mechanisms and Treatment Outcomes in Sub-Saharan African Populations

Nalongo Bina K.

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 89-94

Malaria remained a leading cause of morbidity and mortality in Sub-Saharan Africa, where Plasmodium falciparum demonstrates increasing resistance to multiple antimalarial agents. The molecular basis of this resistance involved complex genetic mutations affect...

2026 Faculty of Clinical Medicine and Dentistry

Antimalarial Drug Resistance Mechanisms and Emerging Therapeutic Strategies in Plasmodium falciparum Infection

Nalongo Bina K.

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 95-101

Plasmodium falciparum remained the deadliest malaria parasite, causing over 600,000 deaths annually, with antimalarial drug resistance threatening global control efforts. Multiple resistance mechanisms have emerged against quinolines, antifolates, and artemis...

2026 School of Natural and Applied Sciences

Anaemia and Oxidative Stress: Toxicological Perspectives and Herbal Therapeutics

Nambi Namusisi H.

2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 78-82

Anaemia remains a major global health burden with multifactorial aetiologies including nutritional deficiency, chronic disease, genetic disorders, and toxic exposures. Oxidative stress-an imbalance between pro-oxidant species and antioxidant defenses-plays a...

2026 Faculty of Clinical Medicine and Dentistry

Advances in Vector Control and Gene Drive Technologies for Sustainable Malaria Elimination in Sub-Saharan Africa

Nalongo Bina K.

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 77-83

Malaria transmission in sub-Saharan Africa remained critically dependent on Anopheles mosquito vectors, with existing control strategies including insecticide-treated nets and indoor residual spraying facing challenges from insecticide resistance, behavioral...

2026 School of Natural and Applied Sciences

Adipose Tissue-Derived Exosomes as Nanocarriers in Cancer Progression and Therapy

Katu Amina H.

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 71-76

Adipose tissue derived exosomes are nanoscale extracellular vesicles released by adipocytes, stromal cells, and immune cells within fat depots. In obesity, their secretion rate and molecular cargo shift toward proinflammatory, lipotoxic, and oncogenic profile...

2026 School of Natural and Applied Sciences

Adipose Tissue Immunometabolism as a Unifying Driver of Obesity and Type 2 Diabetes

Katu Amina H.

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 63-70

Adipose tissue is now recognized as an immune organ as much as a fat depot. In obesity, expansion and stress of white adipose tissue (WAT) drive a coordinated rewiring of immune and metabolic pathways “immunometabolism” that links weight gain to insulin resis...

2026 Faculty of Biomedical Sciences

Adipose Tissue Dysfunction in Obesity-Induced Type 2 Diabetes: Mechanistic Insights and Therapeutic Opportunities

Wambui Kibibi J.

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 57-62

Obesity is the strongest modifiable driver of type 2 diabetes (T2D), yet the mechanistic bridge between excess adiposity and systemic dysglycemia is increasingly recognized as dysfunction of adipose tissue (AT) rather than fat mass per se. In health, subcutan...

2025 Faculty of Business and Management

Sustainable Leadership and Business Resilience: Moderating Role of Organisational Culture in the Hospitality Industry

Desmond Oben Neji, Collins Okechukwu Irem, Esther Ugo Alum, Vitalii S. Nitsenko, Green eld Mwakipesile, Gladys Onah Owere, Chukwuoyims Kevin Egwu, Agnes Ugboego Chukwu, Kingsley Sunday Uzoadigonma Oyekezie, Chichi Maureen Anyalor

2025 | Discover Sustainability | Pp. 1-22

The resilience of hospitality businesses has received scholarly attention due to the role the businessesplay in the economic development of every country. Previous studies on the resilience of hospitalitybusinesses have not examined how sustainable leadership...

2025 School of Pharmacy

Prevalence and Predictors of Cognitive Decline among Diabetes Mellitus Patients Attending Jinja Regional Referral Hospital: A Cross‐Sectional Study in Eastern Uganda

Jasper Silver Makasi, Narayana Goruntla, Bhavana Reddy Bommireddy, Bhavani Mopuri, Easwaran Vigneshwaran, Mohammad Jaffar Sadiq Mantargi, Vishnuvandana Bandaru, Joseph Obiezu Chukwujekwu Ezeonwumelu, Tadele Mekuriya Yadesa

2025 | Health Science Reports | Pp. 1-13

Background: Human immunodeficiency infections have remained one of the major public health threats globally, with pronounced effects in Sub-Saharan Africa and Asia. Globally, more than 300 children and adolescents succumb to HIV/AIDS every day, with experts a...

2025 Faculty of Biomedical Sciences

Potential Effect of Fisetin and Curcumin Combination in Alleviating Arsenic Trioxide–Mediated Oxidative Stress and Hepatotoxicity

Ezinne Chidinma Oviosun, Augustine Oviosun, Esther Omonye-Abai Shelu, Kenechukwu Emmanuel Nwanama, Nkechi Mercy Okoye, Osebhagimede Favour Ulikhifun

2025 | The Journal of Anatomical Sciences | Pp. 132-142

Arsenic trioxide (As2O3) exposure remains a major public health concern due to its hepatotoxic effects, which are largely mediated by oxidative stress, inflammation, and apoptosis. Natural bioactive compounds such as Fisetin, a flavonoid found in strawberries...