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2025 School of Pharmacy

Enhancing Healthcare Capacity for Arthritis Management: A Comprehensive Approach to Training Healthcare Workers in West Africa

Abaho Areeba Fortunate

2025 | IDOSR JOURNAL OF SCIENTIFIC RESEARCH | Pp. 133-137

Arthritis, encompassing a spectrum of musculoskeletal disorders including osteoarthritis (OA), rheumatoid arthritis (RA), and other inflammatory conditions, is increasingly recognized as a significant public health challenge in West Africa. Despite its rising...

2025 Faculty of Biomedical Sciences

Antimalarial Medicinal Plants: Evidence and Gaps

Nakawungu Catherine

2025 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 10-20

Malaria remains a global health burden, particularly in sub-Saharan Africa, where rising drug resistance and treatment costs necessitate alternative therapeutic strategies. Medicinal plants, long central to traditional medicine, represent a valuable reservoir...

2025 School of Pharmacy

Targeting the Plasmodium Lifecycle: Advances and Challenges in Antimalarial Drug Development

Twesigye Davis

2025 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 95-100

Malaria remains one of the world’s most devastating infectious diseases, caused by Plasmodium parasites transmitted through Anopheles mosquitoes. Despite global efforts to reduce its burden, resistance to existing antimalarial drugs threatens to reverse progr...

2025 School of Pharmacy

Targeting Oxidative Stress and Immunomodulation in Metabolic and Endocrine Disorders: Lessons from Benign Prostatic Hyperplasia, Diabetes, and Reproductive Hormone Imbalance

Muhindo Anitah

2025 | IDOSR JOURNAL OF SCIENTIFIC RESEARCH | Pp. 29-34

Metabolic and endocrine disorders share a set of conserved pathogenic circuits in which oxidative stress and immune dysregulation are tightly intertwined. Benign prostatic hyperplasia (BPH), diabetes mellitus, and reproductive hormone imbalance provide comple...

2025 Faculty of Biomedical Sciences

Role of Natural Products in Targeting Mitochondrial Dysfunction and Energy Metabolism in Obesity-Associated Diabetes

Bwambale Isaac

2025 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 153-161

Obesity-associated diabetes, often referred to as diabesity, is a rapidly growing global health challenge characterized by impaired glucose homeostasis, insulin resistance, and progressive mitochondrial dysfunction. Mitochondria are central regulators of ener...

2025 Faculty of Biomedical Sciences

Role of Nanodiagnostics in Early Cancer Detection: Advances in Biosensors and Imaging Technologies

Bwambale Isaac

2025 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 145-152

Early detection of cancer significantly improves therapeutic outcomes, enhances patient survival rates, and reduces treatment costs. However, conventional diagnostic tools often lack the sensitivity and specificity required to detect tumors at their incipient...

2025 School of Pharmacy

Role of Marine-Derived Bioactive Compounds in Combating Obesity-Linked Diabetes (Diabesity): Emerging Evidence and Future Perspectives

Kabazzi Douglas T.

2025 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 137-144

The global rise of obesity and type 2 diabetes mellitus (T2DM), collectively referred to as diabesity, represents one of the most pressing health challenges of the twenty-first century. These intertwined metabolic disorders share common pathophysiological fea...

2025 School of Pharmacy

Roads and Malaria Transmission: Unveiling the Epidemiological Impacts of Transport Infrastructure on Anopheles Mosquito Ecology in Sub-Saharan Africa

Omagor Jacob

2025 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 132-136

Transport networks such as roads and highways are essential for economic growth and connectivity, yet their unintended ecological consequences can exacerbate malaria transmission dynamics. This review explores the multifaceted role of road construction and ma...

2025 School of Pharmacy

Polyphenols as Dual Modulators of Insulin Sensitivity and Lipid Metabolism in Obese Diabetic Patients

Namirimu Sandrah

2025 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 120-131

Obesity and type 2 diabetes mellitus (T2DM) constitute two of the most pervasive and interconnected metabolic disorders worldwide. Characterized by insulin resistance and dysregulated lipid metabolism, these conditions contribute to cardiovascular disease, he...

2025 School of Pharmacy

Polyphenolic Compounds from Natural Products in the Dual Management of Obesity and Diabetes: Mechanistic Insights and Therapeutic Potential

Waiswa Arajab

2025 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 109-119

Obesity and type 2 diabetes mellitus (T2DM) are tightly interlinked metabolic disorders characterized by insulin resistance, chronic low-grade inflammation, and dysregulated energy homeostasis. Together they form a convergent pathophysiological entity often t...