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2026 School of Pharmacy

Dual GLP-1/GIP Agonists for Weight Reduction and Cardiovascular Outcomes in Type 2 Diabetes

Ernest Nsubuga

2026 | IAA Journal of Scientific Research | Pp. 65-70

Type 2 diabetes mellitus (T2DM) was characterized by hyperglycemia and frequently accompanied by obesity and elevated cardiovascular risk. Incretin hormone-based therapies, especially glucagon-like peptide-1 receptor agonists (GLP-1 RAs), had demonstrated eff...

2026 School of Pharmacy

Dual GIP/GLP-1 Receptor Agonists for Type 2 Diabetes: Efficacy and Metabolic Benefits

Ernest Nsubuga

2026 | IAA Journal of Scientific Research | Pp. 55-64

Type 2 diabetes mellitus represented a global metabolic crisis characterized by progressive beta cell dysfunction, insulin resistance, and chronic hyperglycemia. Traditional incretin-based therapies targeting glucagon-like peptide 1 (GLP-1) receptors have dem...

2026 School of Pharmacy

Diabetes and Oral Health: Evidence, Mechanisms, and Clinical Implications

Arionget Jemima

2026 | IAA Journal of Scientific Research | Pp. 41-54

Diabetes mellitus is a chronic metabolic disorder with wide-ranging systemic consequences, including profound effects on oral health. Accumulating evidence demonstrates a bidirectional relationship between diabetes and oral diseases, particularly periodontal...

2026 School of Pharmacy

Diabetes and Amputation: Prevention and Care

Arionget Jemima

2026 | IAA Journal of Scientific Research | Pp. 32-40

Diabetes mellitus is a major global public health challenge and a leading cause of non-traumatic lower-extremity amputations worldwide. The burden of diabetes-related amputation is driven primarily by preventable complications, notably diabetic foot ulcers ar...

2026 School of Pharmacy

Cybersecurity Challenges and Solutions for Mobile Money Platforms in East Africa

Arionget Jemima

2026 | IAA Journal of Scientific Research | Pp. 28-31

Mobile money platforms have revolutionized financial inclusion in East Africa, enabling millions of previously unbanked individuals to access digital financial services. Platforms such as M-Pesa, MTN Mobile Money, and Tigo Pesa have facilitated financial tran...

2026 School of Pharmacy

Cultural Beliefs and Misconceptions about Cancer in Eastern Nigeria

Taliikwa Nicholas Ceaser

2026 | IAA Journal of Scientific Research | Pp. 23-27

Cancer continues to pose a significant public health challenge in Eastern Nigeria, where cultural beliefs, traditional practices, and religious interpretations strongly influence perceptions of the disease. Misconceptions about cancer causation, prevention, a...

2026 School of Pharmacy

CRISPR-Nanoparticle Delivery Systems for Gene Editing of Obesity and Diabetes Targets

Mpora Kakwanzi Evelyn

2026 | IAA Journal of Applied Sciences | Pp. 119-126

Obesity and type 2 diabetes mellitus (T2DM) are complex polygenic diseases in which environmental factors act on a susceptible genomic background to drive chronic energy imbalance, insulin resistance and β-cell failure. Although current pharmacotherapies impr...

2026 School of Pharmacy

CRISPR-Cas9 Gene Editing to Achieve HIV Cure: Current Progress and Barriers

Taliikwa Nicholas Ceaser

2026 | IAA Journal of Scientific Research | Pp. 12-17

Human immunodeficiency virus type 1 persisted as a global health challenge affecting approximately 39 million individuals worldwide, with current antiretroviral therapy requiring lifelong adherence while failing to eliminate latent viral reservoirs. CRISPR-Ca...

2026 School of Pharmacy

CRISPR-Cas9 Gene Editing for Restoring Pancreatic Beta Cell Function in Diabetes

Taliikwa Nicholas Ceaser

2026 | IAA Journal of Scientific Research | Pp. 18-22

Diabetes mellitus remained a leading metabolic disorder characterized by impaired insulin production and secretion due to β-cell dysfunction or loss. Conventional pharmacotherapy alleviates hyperglycemia but does not restore endogenous β-cell mass. The discov...

2026 School of Pharmacy

CRISPR-Cas9 Gene Editing for Monogenic Diabetes: Therapeutic Potential and Clinical Challenges

Zakaria Ali

2026 | IAA Journal of Scientific Research | Pp. 1-11

Monogenic diabetes mellitus comprised a heterogeneous group of disorders caused by single-gene mutations affecting pancreatic β-cell function or insulin action, accounting for approximately 1--2% of all diabetes cases yet frequently misdiagnosed as type 1 or...