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2026 School of Pharmacy

GLP-1 Receptor Agonist and SGLT2 Inhibitor Combination Therapy in Type 2 Diabetes Management

Mercy Latricia

2026 | IAA Journal of Biological Sciences | Pp. 45-54

Type 2 diabetes mellitus (T2DM) affects approximately 537 million adults globally, with projections indicating 783 million cases by 2045, driving substantial cardiovascular and renal morbidity. Monotherapy with glucagon-like peptide-1 receptor agonists (GLP-1...

2026 School of Pharmacy

GLP-1 Receptor Agonist and SGLT2 Inhibitor Combination Therapy in Type 2 Diabetes Management: Biochemical Mechanisms, Clinical Efficacy, and Translational Implications

Mercy Latricia

2026 | IAA Journal of Biological Sciences | Pp. 55-59

Combination therapy with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and sodium–glucose cotransporter 2 inhibitors (SGLT2 inhibitors) has emerged as a strategic approach for glycemic control, weight management, and cardiovascular risk modification i...

2026 School of Pharmacy

Global Health Partnerships in Action: Evaluating the Impact of WHO, UNAIDS, and the Global Fund on HIV/AIDS Prevention and Treatment in East Africa

Nasira A. Sitar

2026 | IAA Journal of Biological Sciences | Pp. 40-44

The HIV/AIDS epidemic remains a major public health challenge in East Africa, with countries such as Uganda, Kenya, Tanzania, Rwanda, Burundi, and Ethiopia disproportionately affected. Global health partnerships, particularly the World Health Organization (WH...

2026 School of Pharmacy

Global Governance and HIV/AIDS Policy in East Africa: The Influence of International Organizations

Nasira A. Sitar

2026 | IAA Journal of Biological Sciences | Pp. 36-39

The HIV/AIDS epidemic has posed significant public health, social, and economic challenges in East Africa over the past three decades. International organizations—including UNAIDS, PEPFAR, the Global Fund, and the World Bank—have played a central role in shap...

2026 School of Pharmacy

Gene Drive Technology for Anopheles Mosquito Population Control: Ecological Safety and Malaria Elimination Potential

Masika Anna Mahinda

2026 | IAA Journal of Biological Sciences | Pp. 22-28

Malaria remained a devastating parasitic disease, with Anopheles mosquitoes serving as obligate vectors for Plasmodium transmission, accounting for approximately 249 million cases and 608,000 deaths globally in 2022. Traditional vector control strategies face...

2026 School of Pharmacy

Gene Drive Technology for Anopheles Mosquito Control: Mechanisms, Safety, and Ethical Considerations

Masika Anna Mahinda

2026 | IAA Journal of Biological Sciences | Pp. 29-35

Malaria remained a leading cause of morbidity and mortality in tropical regions, with Anopheles mosquitoes serving as the primary vectors. Traditional vector control methods faced challenges including insecticide resistance and operational limitations. Gene d...

2026 School of Pharmacy

Gene Drive Mosquito Release Programs: Population Suppression Strategies for Anopheles gambiae Control

Masika Anna Mahinda

2026 | IAA Journal of Biological Sciences | Pp. 12-21

Malaria remained a leading cause of morbidity and mortality globally, with Anopheles gambiae serving as the primary vector in sub-Saharan Africa where 95% of malaria deaths occur. Traditional vector control methods face increasing challenges from insecticide...

2026 School of Pharmacy

Future Directions in Cancer Genomics Research and Capacity Building in East Africa

Masika Anna Mahinda

2026 | IAA Journal of Biological Sciences | Pp. 8-11

Cancer genomics has transformed cancer diagnosis, treatment, and precision medicine globally, yet East Africa remains underrepresented in these advancements. This review examines the current landscape of cancer genomics research and capacity in East African c...

2026 School of Pharmacy

Ferroquine as Next-Generation Antimalarial: Pharmacology, Resistance Profiles, and Clinical Development

Muhindo Edgar

2026 | IAA Journal of Biological Sciences | Pp. 1-7

Malaria remained a global health crisis, with increasing resistance to conventional antimalarials including chloroquine and artemisinin derivatives, threatening disease control efforts. Ferroquine, a ferrocene-containing derivative of chloroquine, represents...

2026 School of Pharmacy

Extracellular Vesicles from Obese Adipose Tissue: Hidden Messengers in the Onset of Type 2 Diabetes

Muhindo Edgar

2026 | IAA Journal of Scientific Research | Pp. 141-147

Adipose tissue is now recognized as a complex immuno-endocrine organ that communicates with distant metabolic tissues through hormones, lipids and, increasingly appreciated, extracellular vesicles (EVs). In obesity, expanding adipose depots become inflamed, h...