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2025 School of Pharmacy

Effectiveness of CRISPR-Modified Mosquitoes Versus Insecticide-Treated Nets in Reducing Malaria Transmission: A Review

Ivan Mutebi

2025 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 91-94

Malaria remains a major global health challenge, particularly in sub-Saharan Africa, where conventional vector control strategies such as insecticide-treated nets (ITNs) have significantly reduced morbidity and mortality. However, emerging pyrethroid resistan...

2025 School of Pharmacy

Effect of CRISPR-Cas9 Beta-Cell Editing versus Insulin Therapy on Glycemic Control in Type 1 Diabetic Adults: A Narrative Review

Omagor Jacob

2025 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 69-72

Type 1 diabetes mellitus (T1DM) is an autoimmune disorder leading to beta-cell destruction and absolute insulin deficiency, necessitating lifelong insulin therapy. While insulin therapy remains the standard for glycaemic control, it does not address the under...

2025 School of Pharmacy

Drains and Disease: The Role of Urban Water Management Systems in Shaping Anopheles Mosquito Habitats

Mukisa Ian Mugaiga

2025 | IDOSR JOURNAL OF SCIENTIFIC RESEARCH | Pp. 24-28

Urbanization has dramatically altered the hydrological landscape, with poorly designed or neglected drainage systems becoming hotspots for Anopheles mosquito breeding. This review evaluates the role of water management infrastructure—storm drains, ditches, cu...

2025 Faculty of Clinical Medicine and Dentistry

Digital Tools and E-Learning Platforms for Diabetes Education in Remote East Africa: Opportunities and Limitations

Ernest Nsubuga

2025 | IDOSR JOURNAL OF SCIENTIFIC RESEARCH | Pp. 15-18

The rising prevalence of diabetes in East Africa poses significant public health challenges, particularly in remote rural areas where healthcare infrastructure and trained professionals are limited. Digital tools and e-learning platforms have emerged as promi...

2025 School of Pharmacy

Digital Health Interventions for Gestational Diabetes Management in Low-Resource Settings

Arionget Jemima

2025 | IDOSR JOURNAL OF SCIENTIFIC RESEARCH | Pp. 11-14

Gestational diabetes mellitus (GDM) is a rising public health concern in low-resource settings, where limited infrastructure and workforce shortages hinder effective screening, diagnosis, and management. Poorly controlled GDM increased risks of maternal compl...

2025 School of Pharmacy

Diarrheal Outbreaks in Nigerian Refugee Camps: Causes and Interventions

Taliikwa Nicholas Ceaser

2025 | IDOSR JOURNAL OF SCIENTIFIC RESEARCH | Pp. 7-10

Diarrheal diseases are a major public health concern in Nigerian refugee camps, where displaced populations face overcrowding, poor sanitation, limited water supply, and malnutrition, creating conditions conducive to recurrent outbreaks. This review examines...

2025 School of Pharmacy

CRISPR-Engineered Anopheles Mosquitoes for Malaria Transmission Interruption: A Review of Preclinical and Early Field Evidence

Kabazzi Douglas T.

2025 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 82-85

Malaria remains a leading cause of morbidity and mortality in endemic regions, driven largely by Plasmodium falciparum transmission via Anopheles mosquitoes. Current vector control tools face diminishing effectiveness due to insecticide resistance and operati...

2025 School of Pharmacy

CRISPR-Cas9 Gene Drive Systems for Malaria Vector Control: Progress and Implementation Challenges

Kabazzi Douglas T.

2025 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 73-76

Malaria remains a leading public health threat, with more than 249 million cases and over 600,000 deaths reported globally in 2022, primarily in sub-Saharan Africa. Traditional vector control tools such as insecticide-treated nets and indoor residual spraying...

2025 School of Pharmacy

CRISPR-Cas Gene Editing Strategies for HIV Reservoir Eradication and Functional Cure

Namirimu Sandrah

2025 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 64-68

Human immunodeficiency virus (HIV) persists in latent reservoirs despite effective antiretroviral therapy, presenting a fundamental barrier to achieving a functional cure. The emergence of clustered regularly interspaced short palindromic repeats and CRISPR-a...

2025 School of Pharmacy

CRISPR-Cas Gene Editing Approaches for HIV Reservoir Elimination and Functional Cure Strategies

Omagor Jacob

2025 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 59-63

Human immunodeficiency virus (HIV) infection remains a global health challenge, with more than 38 million individuals living with the virus worldwide in 2023. Despite antiretroviral therapy (ART) effectively suppressing viral replication, latent reservoirs of...